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Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombinationSAKATA, Koh-Ichi; SOMEYA, Masanori; MATSUMOTO, Yoshihisa et al.Cancer science. 2011, Vol 102, Num 9, pp 1712-1716, issn 1347-9032, 5 p.Article

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La dihydropyrimidine déshydrogénase intratumorale et son inhibition : une nouvelle approche dans la pharmacomodulation du 5-fluoro-uracile = Intratumoral dihydropyrimidine dehydrogenase and its inhibition:a new approach involving 5-fluorouracilmodulationMILANO, G; ETIENNE, M. C; FISCHEL, J. L et al.Annales de gastroénterologie et d'hépatologie. 1995, Vol 31, Num 2, pp 103-105, issn 0066-2070Article

A mild phenotype of dihydropyrimidine dehydrogenase deficiency and developmental retardation associated with a missense mutation affecting cofactor bindingWEIDENSEE, Sabine; GOETTIG, Peter; BERTONE, Marko et al.Clinical biochemistry. 2011, Vol 44, Num 8-9, pp 722-724, issn 0009-9120, 3 p.Article

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Dihydropyrimidine déshydrogénase: identification des ADN complémentaires à partir du foie de bovin et des lymphocytes humains: bases moléculaires de la pharmacogénétique du 5-Fluorouracile = cDNA cloning of dihydrophyrimidine dehydrogenase (DPD) from bovine liver and human lymphocytes: genetic bases of the pharmacogenetic syndrom involving 5-FluorouracilAlbin, Nicolas; Gouyette, A.1996, 220 p.Thesis

Dihydropyrimidine dehydrogenase deficiency presenting with psychomotor retardation and ocular abnormalitiesBAKKER, H. D; RUBIO GOZALBO, M. E; VAN GENNIP, A. H et al.Journal of inherited metabolic disease. 1994, Vol 17, Num 5, pp 640-641, issn 0141-8955Article

Comparative Functional Analysis of DPYD Variants of Potential Clinical Relevance to Dihydropyrimidine Dehydrogenase ActivityOFFER, Steven M; FOSSUM, Croix C; WEGNER, Natalie J et al.Cancer research (Chicago, Ill.). 2014, Vol 74, Num 9, pp 2545-2554, issn 0008-5472, 10 p.Article

Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicityVAN KUILENBURG, André B. P; MEIJER, Judith; KLÜMPEN, Heinz-Josef et al.Human genetics. 2010, Vol 128, Num 5, pp 529-538, issn 0340-6717, 10 p.Article

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Dépistage des patients déficitaires en dihydropyrimidine déhydrogénase avant traitement par fluoropyrimidines : Optimisation des traitements anticancéreux de l'enfant et de l'adulte = Detection of dihydropyrimidine dehydrogenase deficiency before treatment by fluoropyrimidinesGAMELIN, Erick; BOISDRON-CELLE, Michèle; MOREL, Alain et al.Thérapie (Paris). 2007, Vol 62, Num 2, pp 99-103, issn 0040-5957, 5 p.Conference Paper

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Identification of a four-base deletion (deITCAT_296-299) in the dihydropyrimidine dehydrogenase gene with variable clinical expressionVREKEN, P; VAN KUILENBURG, A. B. P; MEINSMA, R et al.Human genetics. 1997, Vol 100, Num 2, pp 263-265, issn 0340-6717Article

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A DPYD Variant (Y186C) in Individuals of African Ancestry Is Associated With Reduced DPD Enzyme ActivityOFFER, S. M; LEE, A. M; MATTISON, L. K et al.Clinical pharmacology and therapeutics. 2013, Vol 94, Num 1, pp 158-166, issn 0009-9236, 9 p.Article

Activator protein accelerates dihydropyrimidine dehydrogenase gene transcription in cancer cellsUKON, Kei; TANIMOTO, Keiji; SHIMOKUNI, Tatsushi et al.Cancer research (Baltimore). 2005, Vol 65, Num 3, pp 1055-1062, issn 0008-5472, 8 p.Article

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Effect of nitrogen source on pyrimidine catabolism by Pseudomonas fluorescensSANTIAGO, M. F; WEST, T. P.Microbiological research. 1999, Vol 154, Num 3, pp 221-224, issn 0944-5013Article

Identification and tissue-specific expression of a NADH-dependent activity of dihydropyrimidine dehydrogenase in manVAN KUILENBURG, A. B. P; VAN LENTHE, H; VAN GENNIP, A. H et al.Anticancer research. 1996, Vol 16, Num 1, pp 389-394, issn 0250-7005Article

Inhibition of dihydropyrimidine dehydrogenase by 5-propynyluracil, a metabolite of the anti-varicella zoster virus agent netivudinePECK, R; WIGGS, R; CALLAGHAN, J et al.Clinical pharmacology and therapeutics. 1996, Vol 59, Num 1, pp 22-31, issn 0009-9236Article

5-Ethynyluracil (776C85) : inactivation of dihydropyrimidine dehydrogenase in vivoSPECTOR, T; HARRINGTON, J. A; PORTER, D. J. T et al.Biochemical pharmacology. 1993, Vol 46, Num 12, pp 2243-2248, issn 0006-2952Article